Mast Cell Activation Syndrome occurs when mast cells become overly sensitive and release excessive inflammatory chemicals. This overreaction can be triggered by various internal and external factors, leading to widespread symptoms. Identifying the root causes is essential for managing the condition effectively.
Immune System Dysregulation
When the immune system is constantly overstimulated due to infections, chronic stress, or autoimmune conditions, mast cells become hyperactive. This leads to excessive inflammation, making the body more reactive to even minor triggers.
Environmental Toxin Exposure
Chemicals, heavy metals and air pollutants can overstimulate mast cells, causing them to release histamine and other inflammatory mediators. Long-term exposure weakens the body’s ability to regulate mast cell activity, leading to chronic symptoms.
Nervous System Imbalance
The nervous system plays a key role in regulating mast cell function. High levels of emotional stress, trauma, or nervous system dysfunction can make mast cells hypersensitive, leading to unpredictable reactions and heightened inflammation.
Mast Cell Activation Syndrome can make daily life unpredictable, as common triggers like food, scents, or stress can cause flare-ups. Symptoms such as fatigue, itching, dizziness, and breathing issues can disrupt work, social life, and mental well-being. The constant need for caution often leads to stress and lifestyle limitations.
To manage symptoms, individuals may need to:
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